5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine

5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine - Names and Identifiers

Name	1H-Pyrrolo[2,3-b]pyridine, 5-(4-chlorophenyl)-
Synonyms	918516-27-5 5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine 1H-Pyrrolo[2,3-b]pyridine, 5-(4-chlorophenyl)-
CAS	918516-27-5

5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine - Physico-chemical Properties

Molecular Formula	C13H9ClN2
Storage Condition	Room Temprature

5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine - Introduction

1H-Pyrrolo[2,3-b]pyridine, 5-(4-chlorophenyl)-is an organic compound with the chemical formula C11H7ClN.

Nature:
-Appearance: Colorless to light yellow crystal
-Melting Point: 163-165°C
-Boiling point: 472.6°C
-Molecular Weight: 205.634
-Solubility: Soluble in most organic solvents such as dichloromethane and dimethyl sulfoxide, insoluble in water.

Use:
1H-Pyrrolo[2,3-b]pyridine, 5-(4-chlorophenyl)-is an important intermediate, often used in organic synthesis, especially for the synthesis of indole compounds and natural products. It has a wide range of potential applications in the field of medicine, and may have anti-tumor, anti-inflammatory and antibacterial activities.

Method:
The synthesis method of 1H-Pyrrolo[2,3-b]pyridine, 5-(4-chlorophenyl)-mainly includes the following steps:
1. take 1-methyl pirlindole as starting material, and sodium nitrite reaction to generate 1-nitrosopirindole.
2. the palladium-catalyzed Grignard reaction of 1-nitrosopirindole and 4-chlorobenzene boronic acid gave the target product 1H-Pyrrolo[2,3-b]pyridine, 5-(4-chlorophenyl)-.

Safety Information:
1H-Pyrrolo[2,3-b]pyridine, 5-(4-chlorophenyl)-Toxicity data are very limited and require appropriate laboratory safety measures at the time of use, including protective glasses, gloves, and laboratory coats. At the same time, please evaluate the safety of the chemical substance in the laboratory environment according to the safety data sheet (SDS) of the chemical substance and follow the laboratory safety operating procedures.

Last Update：2024-04-09 21:11:58